BDBM50141344 3-[3-Chloro-4-(3-guanidino-benzoylamino)-phenyl]-acrylic acid::CHEMBL442541

SMILES [#7]\[#6](-[#7])=[#7]/c1cccc(c1)-[#6](=O)-[#7]-c1ccc(-[#6]=[#6]-[#6](-[#8])=O)cc1Cl

InChI Key InChIKey=KALOYQBAVHVFJS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50141344   

TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141344(3-[3-Chloro-4-(3-guanidino-benzoylamino)-phenyl]-a...)
Affinity DataIC50:  426nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141344(3-[3-Chloro-4-(3-guanidino-benzoylamino)-phenyl]-a...)
Affinity DataIC50:  5.90nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141344(3-[3-Chloro-4-(3-guanidino-benzoylamino)-phenyl]-a...)
Affinity DataIC50:  60nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141344(3-[3-Chloro-4-(3-guanidino-benzoylamino)-phenyl]-a...)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141344(3-[3-Chloro-4-(3-guanidino-benzoylamino)-phenyl]-a...)
Affinity DataIC50:  11nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed