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BDBM50142088 3'-Piperazin-1-yl-biphenyl-4-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenyl]-amide::CHEMBL178112

SMILES: Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2cccc(c2)N2CCNCC2)nc1

InChI Key: InChIKey=JBIFABOLUMVXGZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142088   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50142088
PNG
(3'-Piperazin-1-yl-biphenyl-4-carboxylic acid [4-ch...)
Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2cccc(c2)N2CCNCC2)nc1
Show InChI InChI=1S/C29H25Cl2N5O2/c30-22-8-10-26(25(17-22)29(38)35-27-11-9-23(31)18-33-27)34-28(37)20-6-4-19(5-7-20)21-2-1-3-24(16-21)36-14-12-32-13-15-36/h1-11,16-18,32H,12-15H2,(H,34,37)(H,33,35,38)
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Article
PubMed
n/an/a 39n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against coagulation factor Xa.


Bioorg Med Chem Lett 14: 983-7 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.079
BindingDB Entry DOI: 10.7270/Q21V5DF7
More data for this
Ligand-Target Pair