BDBM50142331 ({4-[2-Benzotriazol-1-yl-3-(4-bromo-phenyl)-2-phenyl-propyl]-phenyl}-difluoro-methyl)-phosphonic acid::CHEMBL9339

SMILES OP(O)(=O)C(F)(F)c1ccc(CC(Cc2ccc(Br)cc2)(c2ccccc2)n2nnc3ccccc23)cc1

InChI Key InChIKey=VVHNEMAMQJWZGQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142331   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142331(({4-[2-Benzotriazol-1-yl-3-(4-bromo-phenyl)-2-phen...)
Affinity DataIC50:  89nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142331(({4-[2-Benzotriazol-1-yl-3-(4-bromo-phenyl)-2-phen...)
Affinity DataIC50:  92nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142331(({4-[2-Benzotriazol-1-yl-3-(4-bromo-phenyl)-2-phen...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142331(({4-[2-Benzotriazol-1-yl-3-(4-bromo-phenyl)-2-phen...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed