BDBM50142335 CHEMBL274435::[(4-{4-Benzotriazol-1-yl-5-[4-(difluoro-phosphono-methyl)-phenyl]-4-phenyl-pent-1-enyl}-phenyl)-difluoro-methyl]-phosphonic acid
SMILES OP(O)(=O)C(F)(F)c1ccc(CC(C\C=C\c2ccc(cc2)C(F)(F)P(O)(O)=O)(c2ccccc2)n2nnc3ccccc23)cc1
InChI Key InChIKey=IQWGAAHPACZIDQ-VOTSOKGWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50142335
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair