BDBM50142701 CHEMBL285479

SMILES C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

InChI Key InChIKey=FHZPGIUBXYVUOY-XDGMXVDYSA-N

Data  2 KI  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50142701   

TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataKi:  2.17E+3nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataKi: >4.00E+4nMAssay Description:Binding affinity to DOP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataEC50:  372nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataIC50: >1.50E+4nMAssay Description:Antagonist activity at mouse vas deferns MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as dynamic mass redistribution by DMR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataIC50: >4.00E+3nMAssay Description:Antagonist activity at guinea pig ileum MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataIC50:  37nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataIC50:  1.25E+3nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50142701(CHEMBL285479)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of calcium mobilization by Fluo-4 AM dye based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed