BDBM50143106 6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine::CHEMBL50581

SMILES C(Oc1nn2c(nnc2c2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=IFBAGWIMPPBASO-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50143106   

TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  16nMAssay Description:Binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  38nMAssay Description:Binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  38nMAssay Description:Binding affinity to recombinant human GABA-A alpha5beta3gamma2 receptor expressed in L(tk) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  41nMAssay Description:Binding affinity for human GABA-A receptor alpha3-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  41nMAssay Description:Binding affinity to recombinant human GABA-A alpha3beta3gamma2 receptor expressed in L(tk) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  280nMAssay Description:Binding affinity to recombinant human GABA-A alpha1beta3gamma2 receptor expressed in L(tk) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50143106(6-Benzyloxy-3-phenyl-[1,2,4]triazolo[3,4-a]phthala...)
Affinity DataKi:  280nMAssay Description:Binding affinity for human GABA-A receptor alpha4-beta3-gamma2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed