BDBM50143735 (2,6-Dichloro-phenyl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone::CHEMBL58441

SMILES CC1(CCN(CC1)C(=O)c1c(Cl)cccc1Cl)N1CCC(CC1)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=UWQOQINSXNYULS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143735   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143735((2,6-Dichloro-phenyl)-(4-diphenylamino-4'-methyl-[...)
Affinity DataIC50:  7.90nMAssay Description:Rises in intracellular [Ca2+] levels by using [Ca2+] sensitive Fluo4 dye in C-C chemokine receptor type 5-transfected CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143735((2,6-Dichloro-phenyl)-(4-diphenylamino-4'-methyl-[...)
Affinity DataIC50:  2.40nMAssay Description:Antagonistic activity against human C-C chemokine receptor type 5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143735((2,6-Dichloro-phenyl)-(4-diphenylamino-4'-methyl-[...)
Affinity DataIC50:  3.5nMAssay Description:Antagonistic activity against monkey C-C chemokine receptor type 5.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed