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BDBM50143925 1-Cyclohexyl-3-decyl-urea::CHEMBL67158::N-CYCLOHEXYL-N'-DECYLUREA::US8815951, 153

SMILES: CCCCCCCCCCNC(=O)NC1CCCCC1

InChI Key: InChIKey=LPXYBLIRYGCMPQ-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143925   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epoxide hydrolase (MsEH)


(Mus musculus (Mouse))
BDBM50143925
PNG
(1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...)
Show SMILES CCCCCCCCCCNC(=O)NC1CCCCC1
Show InChI InChI=1S/C17H34N2O/c1-2-3-4-5-6-7-8-12-15-18-17(20)19-16-13-10-9-11-14-16/h16H,2-15H2,1H3,(H2,18,19,20)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

US Patent
n/an/a 60n/an/an/an/an/an/a



The Regents of the University of California

US Patent


Assay Description
The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...


Citation and Details
More data for this
Ligand-Target Pair
Epoxide hydratase


(Homo sapiens (Human))
BDBM50143925
PNG
(1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...)
Show SMILES CCCCCCCCCCNC(=O)NC1CCCCC1
Show InChI InChI=1S/C17H34N2O/c1-2-3-4-5-6-7-8-12-15-18-17(20)19-16-13-10-9-11-14-16/h16H,2-15H2,1H3,(H2,18,19,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 140n/an/an/an/an/an/a



University of California-Davis

Curated by ChEMBL


Assay Description
Tested for 50 % inhibitory concentration against human soluble epoxide hydrolase (sEH)


J Med Chem 47: 2110-22 (2004)

More data for this
Ligand-Target Pair
Soluble epoxide hydrolase (sEH)


(Mus musculus (Mouse))
BDBM50143925
PNG
(1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...)
Show SMILES CCCCCCCCCCNC(=O)NC1CCCCC1
Show InChI InChI=1S/C17H34N2O/c1-2-3-4-5-6-7-8-12-15-18-17(20)19-16-13-10-9-11-14-16/h16H,2-15H2,1H3,(H2,18,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



University of California-Davis

Curated by ChEMBL


Assay Description
Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH)


J Med Chem 47: 2110-22 (2004)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Epoxide hydrolase 1


(Homo sapiens (Human))
BDBM50143925
PNG
(1-Cyclohexyl-3-decyl-urea | CHEMBL67158 | N-CYCLOH...)
Show SMILES CCCCCCCCCCNC(=O)NC1CCCCC1
Show InChI InChI=1S/C17H34N2O/c1-2-3-4-5-6-7-8-12-15-18-17(20)19-16-13-10-9-11-14-16/h16H,2-15H2,1H3,(H2,18,19,20)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

US Patent
n/an/a 100n/an/an/an/an/an/a



The Regents of the University of California

US Patent


Assay Description
The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...


Citation and Details
More data for this
Ligand-Target Pair