BDBM50143961 CHEMBL62240::N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy)-propyl]-piperidin-4-yl}-N-phenyl-benzamide

SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=HHYUHLAZLCUWCM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143961   

TargetCytochrome P450 2D6(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143961(CHEMBL62240 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...)
Affinity DataKi:  2.00E+3nMAssay Description:Predictive competitive inhibition of cytochrome P450 2D6 was determined in silicoMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50143961(CHEMBL62240 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...)
Affinity DataIC50:  261nMAssay Description:In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed