BDBM50144143 2-{4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-benzoyl]-piperazin-2-yl}-1-morpholin-4-yl-ethanone::CHEMBL65219

SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCOCC1)S(=O)(=O)c1cc2ccc(Cl)cc2s1

InChI Key InChIKey=WEZCXOSTNFUHCF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50144143   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Portola Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144143(2-{4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-[4-...)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144143(2-{4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-[4-...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibitory activity of the compound against thrombin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144143(2-{4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-[4-...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory activity against Coagulation factor X was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed