BDBM50144179 CHEMBL65469::N-(1-Methoxy-6-phenyl-6H-benzo[c]chromen-8-yl)-benzenesulfonamide

SMILES COc1cccc2OC(c3ccccc3)c3cc(NS(=O)(=O)c4ccccc4)ccc3-c12

InChI Key InChIKey=LBPUUYGNAXELAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144179   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144179(CHEMBL65469 | N-(1-Methoxy-6-phenyl-6H-benzo[c]chr...)
Affinity DataIC50:  146nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 61-63 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144179(CHEMBL65469 | N-(1-Methoxy-6-phenyl-6H-benzo[c]chr...)
Affinity DataIC50:  137nMAssay Description:Effect on human Glucocorticoid receptor (GR) in a whole cell assay to measure functional cellular GR-antagonism (GRAF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed