BDBM50144663 2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl)-3-[3-4-methanesulfonylamino-benzyl)-thioureido-N-hydroxy]-propyl ester::CHEMBL308999

SMILES Cc1ccc(CC(COC(=O)C(C)(C)C)CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1C

InChI Key InChIKey=BJVPJHIGBXMZDK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144663   

TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50144663(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  1.04E+3nMAssay Description:Binding affinity towards rat vanilloid receptor subtype 1 expressed in CHO cells by [3H]-RTX displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50144663(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataIC50:  212nMAssay Description:In vitro antagonist effect against 50 nM capsaicin-induced 45 [Ca2+] influx in vanilloid recptor expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed