BDBM50145021 1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::CHEMBL76758

SMILES C(CCN1CCN(CC1)C1CCCCC1)CC1CCCc2ccccc12

InChI Key InChIKey=TVHNNUAZUKDSIT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50145021   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi:  0.0360nMAssay Description:In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi:  0.0360nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Università

Curated by ChEMBL
LigandPNGBDBM50145021(1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...)
Affinity DataKi: >700nMAssay Description:In vitro binding affinity at serotonin 5-hydroxytryptamine 3 receptor in rat cortex by [3H]-granisetron displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed