BDBM50145906 CHEMBL454662

SMILES COc1ccc(\C=C\C(\O)=C\C(=O)\C=C\c2ccc(OC)cc2)cc1

InChI Key InChIKey=UOIUXHFXWVZDEI-WTJGCYTNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50145906   

TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50145906(CHEMBL454662)
Affinity DataIC50:  530nMAssay Description:Inhibition of human recombinant GSK3-beta using prephosphorylated polypeptide as substrate incubated for 30 mins by Glo-type luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50145906(CHEMBL454662)
Affinity DataIC50:  530nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50145906(CHEMBL454662)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human recombinant BACE1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition incubated for 15 mins by FRET as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed