BDBM50146096 4-{(E)-2-[({[3-(4-Azepan-1-yl-2-methyl-quinolin-8-yloxymethyl)-2,4-dichloro-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-N-methyl-benzamide; Dihydrochloride::CHEMBL542175

SMILES CNC(=O)c1ccc(\C=C\C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(cc(C)nc34)N3CCCCCC3)c2Cl)cc1

InChI Key InChIKey=ALWWZZYTQLZEAK-QGOAFFKASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146096   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146096(4-{(E)-2-[({[3-(4-Azepan-1-yl-2-methyl-quinolin-8-...)
Affinity DataIC50:  840nMAssay Description:Inhibition of specific binding of [3H]BK at 0.06 nM to bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146096(4-{(E)-2-[({[3-(4-Azepan-1-yl-2-methyl-quinolin-8-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of specific binding of [3H]BK at 1 nM to human bradykinin receptor B2 expressed in CHO cells by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed