BDBM50146114 CHEMBL539792::N-(4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-4-piperidin-1-yl-quinolin-8-yloxymethyl)-phenyl]-methyl-carbamoyl}-methyl)-carbamoyl]-vinyl}-phenyl)-isonicotinamide; Trihydrochloride

SMILES CN(C(=O)CNC(=O)\C=C\c1ccc(NC(=O)c2ccncc2)cc1)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)N2CCCCC2)c1Cl

InChI Key InChIKey=ANUKLJHLXUTQKD-LFIBNONCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146114   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146114(CHEMBL539792 | N-(4-{(E)-2-[({[2,4-Dichloro-3-(2-m...)
Affinity DataIC50:  75nMAssay Description:Inhibition of specific binding of [3H]BK at 0.06 nM to bradykinin receptor B2 in guinea pig ileum membrane preparations by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146114(CHEMBL539792 | N-(4-{(E)-2-[({[2,4-Dichloro-3-(2-m...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of specific binding of [3H]BK at 1 nM to human bradykinin receptor B2 expressed in CHO cells by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed