BDBM50146467 CHEMBL99365::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylmethyl)-ethyl]-formamide

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC(=O)CC2)N(O)C=O)c2ccccc2n1

InChI Key InChIKey=YFYQFPIGOKJLFD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146467   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  350nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(CHEMBL99365 | N-Hydroxy-N-[2-[4-(2-methyl-quinolin...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed