BDBM50146470 CHEMBL328199::N-Hydroxy-N-{1-(4-methylene-cyclohexyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(=C)CC2)N(O)C=O)c2ccccc2n1

InChI Key InChIKey=GZISYEQJJGPWOA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50146470   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50:  45nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(CHEMBL328199 | N-Hydroxy-N-{1-(4-methylene-cyclohe...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed