BDBM50146591 CHEMBL3763692

SMILES Fc1ccc(cc1C(F)(F)F)C(=O)Nc1nccn2c(cnc12)-c1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1

InChI Key InChIKey=IRLSPFFMFJRFCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146591   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146591(CHEMBL3763692)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146591(CHEMBL3763692)
Affinity DataIC50: >1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed