BDBM50147464 CHEMBL109977::N-(3-{3-[4-(2-Methoxy-phenyl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-pyrrolo[2,3-b]pyridin-1-yl}-propyl)-formamide

SMILES COc1ccccc1C1=C(C(=O)NC1=O)c1cn(CCCNC=O)c2ncccc12

InChI Key InChIKey=WZVQDLURKRHESY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147464   

TargetProtein kinase C gamma type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147464(CHEMBL109977 | N-(3-{3-[4-(2-Methoxy-phenyl)-2,5-d...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of protein kinase C-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147464(CHEMBL109977 | N-(3-{3-[4-(2-Methoxy-phenyl)-2,5-d...)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibitory concentration against human protein kinase C-betaII using histone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147464(CHEMBL109977 | N-(3-{3-[4-(2-Methoxy-phenyl)-2,5-d...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against rabbit glycogen synthase kinase-3 beta using protein phosphatase inhibitor-2 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed