BDBM50147467 3-[1-(3-Dimethylamino-propyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-naphthalen-1-yl-pyrrole-2,5-dione::CHEMBL326688

SMILES CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2cccc3ccccc23)c2cccnc12

InChI Key InChIKey=WLEWZWNDSXTRLZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50147467   

TargetProtein kinase C alpha type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147467(3-[1-(3-Dimethylamino-propyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory concentration against protein kinase C-alpha using histone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147467(3-[1-(3-Dimethylamino-propyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration against rabbit glycogen synthase kinase-3 beta using protein phosphatase inhibitor-2 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147467(3-[1-(3-Dimethylamino-propyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human protein kinase C etaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147467(3-[1-(3-Dimethylamino-propyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration against human protein kinase C-betaII using histone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147467(3-[1-(3-Dimethylamino-propyl)-1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of protein kinase C-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed