BDBM50147468 3-(7-Azaindolyl)-4-arylmaleimide analogue::CHEMBL423323

SMILES COc1ccccc1C1=C(C(=O)NC1=O)c1cn(CCCNS(N)(=O)=O)c2ncccc12

InChI Key InChIKey=IBTJHABKSWXSHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147468   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147468(3-(7-Azaindolyl)-4-arylmaleimide analogue | CHEMBL...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against rabbit glycogen synthase kinase-3 beta using protein phosphatase inhibitor-2 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147468(3-(7-Azaindolyl)-4-arylmaleimide analogue | CHEMBL...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of protein kinase C-gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50147468(3-(7-Azaindolyl)-4-arylmaleimide analogue | CHEMBL...)
Affinity DataIC50:  890nMAssay Description:Inhibitory concentration against human protein kinase C-betaII using histone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed