BDBM50148238 CHEMBL3765037

SMILES [H][C@@]12CC=CC[C@]1([H])C(=NN(C1CCCCCC1)C2=O)c1ccc(OC)c(OCCCCOc2ccc(cc2)-n2ccnc2)c1

InChI Key InChIKey=FLCHWTIQFVHCMK-IOWSJCHKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148238   

TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148238(CHEMBL3765037)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50148238(CHEMBL3765037)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed