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BDBM50148274 CHEMBL3769490

SMILES: CC(=O)c1cc(-c2ccccc2O)c2ccccn12

InChI Key: InChIKey=LZLQZXYENRVRHD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148274   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain adjacent to zinc finger domain protein 2B


(Homo sapiens (Human))
BDBM50148274
PNG
(CHEMBL3769490)
Show SMILES CC(=O)c1cc(-c2ccccc2O)c2ccccn12
Show InChI InChI=1S/C16H13NO2/c1-11(18)15-10-13(12-6-2-3-8-16(12)19)14-7-4-5-9-17(14)15/h2-10,19H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.27E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...


J Med Chem 59: 1410-24 (2016)


Article DOI: 10.1021/acs.jmedchem.5b00209
BindingDB Entry DOI: 10.7270/Q2PK0J09
More data for this
Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2A


(Homo sapiens (Human))
BDBM50148274
PNG
(CHEMBL3769490)
Show SMILES CC(=O)c1cc(-c2ccccc2O)c2ccccn12
Show InChI InChI=1S/C16H13NO2/c1-11(18)15-10-13(12-6-2-3-8-16(12)19)14-7-4-5-9-17(14)15/h2-10,19H,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of recombinant His6-TEV fused human BAZ2A expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...


J Med Chem 59: 1410-24 (2016)


Article DOI: 10.1021/acs.jmedchem.5b00209
BindingDB Entry DOI: 10.7270/Q2PK0J09
More data for this
Ligand-Target Pair