BDBM50148373 5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalene-1,2-diol::CHEMBL326713

SMILES CNCC[C@H](Oc1cccc2c(O)c(O)ccc12)c1cccs1

InChI Key InChIKey=GGNUKUMOMWBKFX-INIZCTEOSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50148373   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  120nMAssay Description:Ability to inhibit [3H]-paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  120nMAssay Description:Ability to inhibit [3H]-mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  695nMAssay Description:Ability to inhibit [3H]-nisoxatine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  695nMAssay Description:Ability to inhibit [3H]-paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  7.27E+3nMAssay Description:Ability to inhibit [3H]-mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]-nisoxatine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed