BDBM50148431 CHEMBL324820::[3-(3-Ethoxy-4-octyloxy-benzylamino)-propyl]-phosphonic acid

SMILES CCCCCCCCOc1ccc(CNCCCP(O)(O)=O)cc1OCC

InChI Key InChIKey=KSAATBXYGYJAQU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50148431   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148431(CHEMBL324820 | [3-(3-Ethoxy-4-octyloxy-benzylamino...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148431(CHEMBL324820 | [3-(3-Ethoxy-4-octyloxy-benzylamino...)
Affinity DataIC50:  74nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 3 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148431(CHEMBL324820 | [3-(3-Ethoxy-4-octyloxy-benzylamino...)
Affinity DataIC50:  12nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 2 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148431(CHEMBL324820 | [3-(3-Ethoxy-4-octyloxy-benzylamino...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 2 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148431(CHEMBL324820 | [3-(3-Ethoxy-4-octyloxy-benzylamino...)
Affinity DataIC50:  420nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed