BDBM50149208 2-Amino-quinolin-8-ol::CHEMBL119647

SMILES Nc1ccc2cccc(O)c2n1

InChI Key InChIKey=UFVLIVCXTIGACT-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149208   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149208(2-Amino-quinolin-8-ol | CHEMBL119647)
Affinity DataKi:  5.60E+4nMAssay Description:Binding affinity towards Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50149208(2-Amino-quinolin-8-ol | CHEMBL119647)
Affinity DataKi:  1.38E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50149208(2-Amino-quinolin-8-ol | CHEMBL119647)
Affinity DataIC50: >2.00E+3nMAssay Description:Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed