BDBM50149843 2''-Amino-6''-(2-benzyloxy-6-hydroxy-phenyl)-1,2,3,4,5,6-hexahydro-[3,4'']bipyridinyl-3''-carbonitrile::CHEMBL361233

SMILES Nc1nc(cc(C2CCCNC2)c1C#N)-c1c(O)cccc1OCc1ccccc1

InChI Key InChIKey=SMBKYSLSHYPLDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149843   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50149843(2''-Amino-6''-(2-benzyloxy-6-hydroxy-phenyl)-1,2,3...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50149843(2''-Amino-6''-(2-benzyloxy-6-hydroxy-phenyl)-1,2,3...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human I-kappa-B-kinase beta (IKK beta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed