BDBM50060582 1,10-Bis(trimethyl ammonium)decane dibromide::1,10-bis-(trimethyl ammonium) decane dibromide::CHEMBL1134::DECAMETHONIUM::DECAMETHONIUM BROMIDE::Decamethonium Iodide::N,N,N'',N''-Tetramethyl-decane-1,10-diammonium; dibromide::N,N,N,N'',N'',N''-Hexamethyldecane-1,10-diammoniumdibromide::Syncurine::decane-1,10-bis(trimethylammonium bromide)
SMILES C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
InChI Key InChIKey=MTCUAOILFDZKCO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50060582
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 460nM ΔG°: -8.64kcal/molepH: 7.0 T: 2°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath
Curated by PDSP Ki Database
University Of Bath
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath
Curated by PDSP Ki Database
University Of Bath
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath
Curated by PDSP Ki Database
University Of Bath
Curated by PDSP Ki Database
Affinity DataKi: 3.50E+3nMAssay Description:Binding affinity to mouse AChEMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 5.73E+3nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair
TargetCholinergic receptor nicotinic alpha 6 subunit(Chick)
University Of Milan
Curated by PDSP Ki Database
University Of Milan
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-6(Chick)
University Of Milan
Curated by PDSP Ki Database
University Of Milan
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Bath
Curated by PDSP Ki Database
University Of Bath
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+6nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of Cryptococccus neoformans H99 PLB1activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMpH: 4.0 T: 2°CAssay Description:The inhibitory activity of the equilibrated mixtures was determined. The activity of AChE was monitored by following the linear change in absorbance...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inhibition of histone H3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 50060582
ITC DataΔG°: -4.06kcal/mole −TΔS°: 1.84kcal/mole ΔH°: -5.97kcal/mole logk: 764
T: 35.05°C
T: 35.05°C
ITC DataΔG°: -3.01kcal/mole −TΔS°: -1.88kcal/mole ΔH°: -1.12kcal/mole logk: 137
T: 35.05°C
T: 35.05°C