BDBM50150210 3-(2-Fluoro-4-methyl-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one::CHEMBL341320

SMILES Cc1ccc(Oc2c(oc(C)cc2=O)-c2ccc(cc2)S(C)(=O)=O)c(F)c1

InChI Key InChIKey=JAIOAMPOGJIYQK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150210   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150210(3-(2-Fluoro-4-methyl-phenoxy)-2-(4-methanesulfonyl...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition concentration against cyclooxygenase-1 (COX-1) in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50150210(3-(2-Fluoro-4-methyl-phenoxy)-2-(4-methanesulfonyl...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibitory concentration for Cyclooxygenase-1 (Prostaglandin G/H synthase 1) in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50150210(3-(2-Fluoro-4-methyl-phenoxy)-2-(4-methanesulfonyl...)
Affinity DataIC50:  60.0nMAssay Description:Inhibitory concentration for Cyclooxygenase-2 (Prostaglandin G/H synthase 2) in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Devi Ahilya Vishwavidyalaya

Curated by ChEMBL
LigandPNGBDBM50150210(3-(2-Fluoro-4-methyl-phenoxy)-2-(4-methanesulfonyl...)
Affinity DataIC50:  60nMAssay Description:Inhibition concentration against cyclooxygenase-2 (COX-2) in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed