BDBM50150767 (2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-hydroxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol::CHEMBL360837

SMILES CCn1nnc(n1)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(N[C@H](CO)Cc3ccc(O)cc3)nc12

InChI Key InChIKey=OPVCMEPGQFSRQW-OIODXMIOSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50150767   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataKi:  140nMAssay Description:Inhibition of [3H]NECA binding to human adenosine A3 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataKi:  600nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataKi:  624nMAssay Description:Inhibition of [3H]DPCPX binding to human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataEC50:  8nMAssay Description:Potency against cAMP formation in CHO cells expressing recombinant human A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataEC50:  1.14E+3nMAssay Description:Relative efficacy against phenylephrine precontracted tissue relaxation in Guinea pig aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Potency against cAMP formation in CHO cells expressing recombinant human A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Iiqab (Csic)

Curated by ChEMBL
LigandPNGBDBM50150767((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataEC50:  2.90nMAssay Description:Efficacy against phenylephrine precontracted tissue relaxation in rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed