BDBM50150842 4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide::CHEMBL185469

SMILES C[C@@H]1CN(CCN1)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1

InChI Key InChIKey=PBZOSRKDAHPMMH-LJQANCHMSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150842   

TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150842(4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboxi...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150842(4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboxi...)
Affinity DataKi:  840nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150842(4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboxi...)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity for human melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150842(4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboxi...)
Affinity DataEC50:  2.70E+3nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150842(4-[((R)-N-Cyclohexyl-3-methyl-piperazine-1-carboxi...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human Melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed