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BDBM50150843 4-(N''''-Cyclohexyl-N'',N''-dipropyl-guanidino)-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide::CHEMBL186189

SMILES: CCCN(CCC)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1

InChI Key: InChIKey=JVEDQEAAHLSYLV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150843   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50150843
PNG
(4-(N''''-Cyclohexyl-N'',N''-dipropyl-guanidino)-N-...)
Show SMILES CCCN(CCC)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1
Show InChI InChI=1S/C28H38Cl2N4O/c1-3-18-34(19-4-2)28(32-24-8-6-5-7-9-24)33-25-14-11-22(12-15-25)27(35)31-17-16-21-10-13-23(29)20-26(21)30/h10-15,20,24H,3-9,16-19H2,1-2H3,(H,31,35)(H,32,33)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
360n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cells


J Med Chem 47: 4083-8 (2004)


Article DOI: 10.1021/jm0400496
BindingDB Entry DOI: 10.7270/Q2JH3KM0
More data for this
Ligand-Target Pair