BDBM50150998 ((4-Methoxy-phenoxycarbonyl)-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-amino)-acetic acid::2-[(4-methoxyphenoxycarbonyl)({3-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)amino]acetic acid::2-[(4-methoxyphenoxycarbonyl)({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)amino]acetic acid::CHEMBL186179::MURAGLITAZAR::MURAGLITAZAR CHLORIDE::[C14]-2-((4-methoxyphenoxy)carbonyl)acetic acid
SMILES COc1ccc(OC(=O)N(CC(O)=O)Cc2ccc(OCCc3nc(oc3C)-c3ccccc3)cc2)cc1
InChI Key InChIKey=IRLWJILLXJGJTD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50150998
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Competitive displacement of fluorescently labelled PPAR tracer ligand from GST-tagged human PPARgamma ligand binding domain after 1 hr in dark by TR-...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.41E+3nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at GAL4 tagged human PPARgamma ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 320nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 4.11E+3nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV-1 by cotransfected with GAL4 by by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 153nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey CV-1 cotransfected with GAL4 by by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Binding affinity to PPARgamma (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.41E+3nMAssay Description:Binding affinity to PPARalpha (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Binding affinity at human PPARalpha by fluorescence polarizationMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Binding affinity at human PPARalpha by fluorescence polarizationMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 1.41E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at human PPARgamma expressed in HEK293 cells assessed as luciferase activity by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Agonist activity at human PPARalpha transactivation expressed in human HePG2 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Agonist activity at human PPARgamma transactivation expressed in human HePG2 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 35nMAssay Description:Agonist activity at PPAR alpha in human HEK cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 247nMAssay Description:Binding affinity at PPAR gamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Agonist activity at PPAR gamma in human HEK cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 188nMAssay Description:Binding affinity at PPAR alpha receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Agonist activity at GAL4-fused PPARalpha assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 595nMAssay Description:Transactivation of human Gal4-fused PPARalpha LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Transactivation of human Gal4-fused PPARgamma LBD expressed in African green monkey COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Sptanis Pharmachem Consulting
Curated by ChEMBL
Sptanis Pharmachem Consulting
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair