BDBM50151001 (S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid::CHEMBL410478

SMILES CC(CC(=O)c1ccccc1)=N[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)C(O)=O

InChI Key InChIKey=LHXYGMFDWCTMSZ-NDEPHWFRSA-N

Data  2 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50151001   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataKi:  1nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human GAL4-tagged PPARgamma chimeric receptor expressed in HEK cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human GAL4-tagged PPARalpha chimeric receptor expressed in HEK cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151001((S)-2-((Z)-1-Methyl-3-oxo-3-phenyl-propenylamino)-...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed