BDBM50151055 CHEMBL3771111

SMILES CCc1ccc(COC(=O)N[C@H]2CNC2=O)cc1

InChI Key InChIKey=RJCKLNSEVMJTHZ-NSHDSACASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151055   

TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151055(CHEMBL3771111)
Affinity DataIC50:  85nMAssay Description:Binding affinity to his-tagged human BRD4 bromodomain1 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151055(CHEMBL3771111)
Affinity DataIC50:  160nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151055(CHEMBL3771111)
Affinity DataIC50:  8.09E+3nMAssay Description:Inhibition of human acid ceramidase by UPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151055(CHEMBL3771111)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed