BDBM50152017 3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL185631

SMILES N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1

InChI Key InChIKey=QIXJCHBQCPESEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152017   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50152017(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor of rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50152017(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of 8-OH DPAT binding to rat hydroxytryptamine 1A receptor expresssed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50152017(3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]-5-HT re-uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed