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BDBM50152149 CHEMBL3780961

InChI string: InChI=1S/C18H17N2.HI/c1-12-15-11-19(2)9-8-13(15)10-17-18(12)14-6-4-5-7-16(14)20(17)3;/h4-11H,1-3H3;1H/q+1;/p-1

SMILES: [I-].Cc1c2c(cc3cc[n+](C)cc13)n(C)c1ccccc21

InChI Key: InChIKey=ABLCIRFOALJFEI-UHFFFAOYSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152149   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Topoisomerase II alpha (HuTopoIIα)


(Homo sapiens (Human))
BDBM50152149
PNG
(CHEMBL3780961)
Show SMILES [I-].Cc1c2c(cc3cc[n+](C)cc13)n(C)c1ccccc21
Show InChI InChI=1S/C18H17N2.HI/c1-12-15-11-19(2)9-8-13(15)10-17-18(12)14-6-4-5-7-16(14)20(17)3;/h4-11H,1-3H3;1H/q+1;/p-1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Vanderbilt University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant human DNA topoisomerase 2alpha expressed in topoisomerase1 deficient Saccharomyces cerevisiae JEL1 assessed as inhibition o...


Bioorg Med Chem Lett 26: 1809-12 (2016)

More data for this
Ligand-Target Pair