BDBM50152518 CHEMBL365908::{1-[4-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid

SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OC[C@H]2COc3ccccc3O2)cc1

InChI Key InChIKey=OCCPUDPMKJXBQC-NRFANRHFSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50152518   

TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataKi:  120nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataKi:  130nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataKi:  1.30E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataKi:  1.30E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataKi:  2.30E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152518(CHEMBL365908 | {1-[4-(2,3-Dihydro-benzo[1,4]dioxin...)
Affinity DataIC50:  270nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed