BDBM50152569 2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid::CHEMBL186181::CHEMBL194519

SMILES OC(=O)C(=O)CC(=O)c1cccc(Oc2ccccc2)c1

InChI Key InChIKey=RSLTYLKWAOZHJA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152569   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50152569(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)
Affinity DataIC50:  1.90E+4nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152569(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)
Affinity DataIC50:  5.44E+3nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50152569(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)
Affinity DataIC50:  7.31E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed