BDBM50152723 3-((R)-2-Amino-2-phenyl-ethyl)-5-[2-(4-tert-butyl-phenyl)-thiazol-4-yl]-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL367806

SMILES Cc1c(-c2csc(n2)-c2ccc(cc2)C(C)(C)C)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F

InChI Key InChIKey=KBKLRZFKELJNLR-MHZLTWQESA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152723   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152723(3-((R)-2-Amino-2-phenyl-ethyl)-5-[2-(4-tert-butyl-...)
Affinity DataKi:  500nMAssay Description:Binding affinity towards cloned human Gonadotropin-releasing hormone receptor expressed in RBL cells was determined by using [125I]-GnRH as radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed