BDBM50153694 CHEMBL3774584

SMILES C[C@@H]1Cc2cc(O)ccc2[C@H](N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F

InChI Key InChIKey=RWZQPEHTNFUUCO-DDRJXTRQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153694   

TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153694(CHEMBL3774584)
Affinity DataIC50:  0.25nMAssay Description:Downregulation of ERalpha in human MCF7 cells incubated for 18 to 22 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153694(CHEMBL3774584)
Affinity DataIC50:  0.970nMAssay Description:Displacement of fluormone ES2 from GST-tagged recombinant human ERalpha LBD after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed