BDBM50154041 (S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl-4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propan-1-one::2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phenyl-1H-imidazol-2-yl)-piperidin-1-yl]-propan-1-one::CHEMBL366311

SMILES Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=MKNJLSBSRYKNIQ-SFTDATJTSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50154041   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataKi:  22nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  500nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  142nMAssay Description:Activity against mu opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  542nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  153nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed