BDBM50154439 5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-carboxylic acid::CHEMBL364321

SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1cccc(O)c1

InChI Key InChIKey=IUNIIGJVJCSRMN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50154439   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase I(Escherichia coli (strain K12))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-integrase is determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HIV-RT is determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed