BDBM50154592 3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-one::3-(2-oxo-2-phenylethylidene)indolin-2-one::CHEMBL190880

SMILES O=C(\C=C1/C(=O)Nc2ccccc12)c1ccccc1

InChI Key InChIKey=HYHFPMWIIOXTBM-RAXLEYEMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154592   

TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50154592(3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Plasmodium falciparum cyclin-dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50154592(3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Competitive inhibition of recombinant TAK1-TAB1 assessed as [33P]gamma-ATP incorporation into substrate histone H1 peptide by filter plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed