BDBM50155764 CHEMBL3780674

SMILES Cl.N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(NC(=O)OCc3ccccc3)c2)cc1

InChI Key InChIKey=PZTIUYOSLCGXHH-UMIAIAFLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155764   

TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50155764(CHEMBL3780674)
Affinity DataIC50:  43nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50155764(CHEMBL3780674)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50155764(CHEMBL3780674)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50155764(CHEMBL3780674)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed