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BDBM50156200 CHEMBL3780274

SMILES: COc1ccc(cc1N1CCNCC1)S(=O)(=O)NCCc1cccc2ccc(F)cc12

InChI Key: InChIKey=FJOCNAUYKRQCHF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156200   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50156200
PNG
(CHEMBL3780274)
Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)NCCc1cccc2ccc(F)cc12
Show InChI InChI=1S/C23H26FN3O3S/c1-30-23-8-7-20(16-22(23)27-13-11-25-12-14-27)31(28,29)26-10-9-18-4-2-3-17-5-6-19(24)15-21(17)18/h2-8,15-16,25-26H,9-14H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 0.690n/an/an/an/an/an/a



Temple University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting method


ACS Med Chem Lett 7: 12-4 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00466
BindingDB Entry DOI: 10.7270/Q2Z89F8F
More data for this
Ligand-Target Pair