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BDBM50156201 CHEMBL3781323

SMILES: COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)NCCc1cccc2ccc(F)cc12

InChI Key: InChIKey=WVXDESJJQIZWPT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156201   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50156201
PNG
(CHEMBL3781323)
Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)NCCc1cccc2ccc(F)cc12
Show InChI InChI=1S/C24H28FN3O3S/c1-27-12-14-28(15-13-27)23-17-21(8-9-24(23)31-2)32(29,30)26-11-10-19-5-3-4-18-6-7-20(25)16-22(18)19/h3-9,16-17,26H,10-15H2,1-2H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 0.280n/an/an/an/an/an/a



Temple University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting method


ACS Med Chem Lett 7: 12-4 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00466
BindingDB Entry DOI: 10.7270/Q2Z89F8F
More data for this
Ligand-Target Pair