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BDBM50156226 CHEMBL3781452

SMILES: COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)NCCc1ccc(F)c2ccccc12

InChI Key: InChIKey=OGSZHERPHIAUIR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156226   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50156226
PNG
(CHEMBL3781452)
Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)NCCc1ccc(F)c2ccccc12
Show InChI InChI=1S/C24H28FN3O3S/c1-27-13-15-28(16-14-27)23-17-19(8-10-24(23)31-2)32(29,30)26-12-11-18-7-9-22(25)21-6-4-3-5-20(18)21/h3-10,17,26H,11-16H2,1-2H3
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Similars

Article
PubMed
n/an/a 0.460n/an/an/an/an/an/a



Temple University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting method


ACS Med Chem Lett 7: 12-4 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00466
BindingDB Entry DOI: 10.7270/Q2Z89F8F
More data for this
Ligand-Target Pair