BDBM50156543 CHEMBL3793045

SMILES [H][C@]12C[C@@H](O)[C@H](COc3cccc(c3)C(F)(F)F)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O

InChI Key InChIKey=LHZBVOUJSPOWKG-HSMRXVHUSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50156543   

TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156543(CHEMBL3793045)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human EP2 receptor expressed in CHO cells assessed as cAMP level by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156543(CHEMBL3793045)
Affinity DataEC50:  9nMAssay Description:Agonist activity at PK2-tagged human EP2 receptor expressed in HEK293 cells assessed as induction of EA-tagged beta-arrestin recruitment incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156543(CHEMBL3793045)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human EP2 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156543(CHEMBL3793045)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293 cells after 24 hrs beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed